Angiotensin II induced contraction of rat and human small intestinal wall musculature in vitro
S Ewert, E Spak, T Olbers, E Johnsson… - Acta …, 2006 - Wiley Online Library
Abstract Background: Angiotensin II (Ang II) is a well‐known activator of smooth muscle in
the vasculature but has been little explored with regard to intestinal wall muscular activity.
This study investigates pharmacological properties of Ang II and expression of its receptors
in small‐intestinal smooth muscle from rats and humans. Methods: Isometric recordings
were performed in vitro on small intestinal longitudinal muscle strips. Protein expressions of
Ang II typ 1 (AT1R) and typ 2 (AT2R) receptors were assessed by Western blot. Results: Ang …
the vasculature but has been little explored with regard to intestinal wall muscular activity.
This study investigates pharmacological properties of Ang II and expression of its receptors
in small‐intestinal smooth muscle from rats and humans. Methods: Isometric recordings
were performed in vitro on small intestinal longitudinal muscle strips. Protein expressions of
Ang II typ 1 (AT1R) and typ 2 (AT2R) receptors were assessed by Western blot. Results: Ang …
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